Question #1
only one answer correct per question
Part 1-
When do they propose that the polybasic cleavage site was added to the SARS-CoV-2 S protein sequence?
in bats
after transmission to humans
in the lab
Part 2-
What do the data suggest for the origin of MERS-CoV?
There was a single jump from camels to humans.
There were multiple independent jumps from camels to humans.
There were multiple independent jumps from bats to humans.
There was a single jump from pangolins to humans.
Part 3-
How do they propose to determine when SARS-CoV-2 jumped to humans?
autopsies of people who died from respiratory illnesses in China
retrospective serological studies
asking the scientists in the Wuhan Lab that created the virus
They say that this cannot be done.
Part 4-
According to the authors, what fact opens the door for the hypothesis that SARS-CoV-2 evolved in a lab during the study of the precursor virus?
It is known that the Wuhan Virology Institute was attempting to make a humanized bat virus.
The bat virus had been passaged in lab for many years.
The pangolin virus had been passaged in lab for many years.
The MERS-CoV virus was being studied in the lab for many years.
Part 5-
how does the acquisition of the three O-linked glycosylation sites argue against evolution by laboratory passage?
Selection for the O-linked glycosylation sites would rely on an immune system.
Selection for the O-linked glycosylation sites would rely on use of antiviral drugs.
Acqusition of the O-linked glycosylation sites would disable the ability of the virus to infect cells.
Acqusition of the O-linked glycosylation sites would disable the ability of the virus to replicate.
References:
Title: The proximal origin of SARS-CoV-2
https://www.nature.com/articles/s41591-020-0820-9
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